Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Drinking contexts associated with early onset of alcohol intoxication among adolescents

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Gendrome Editors' Note: The article below provides the raw material for a proof and is not the proof itself. In addition, the raw material may contain one or more false statements and/or some offensive, outside content.

New research has begun to identify the circumstances by examining relationships between early age of first intoxication (less than 15 years), drinking in different contexts such as one's own home, at friends' homes, or outdoor settings, and problems that arise in those contexts.

Database Proof Substratum: Push-up capacity linked with lower incidence of cardiovascular disease events among men

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Active, middle-aged men able to complete more than 40 push-ups had a significantly lower risk of cardiovascular disease (CVD) outcomes — including diagnoses of coronary artery disease and major events such as heart failure — during 10 years of follow-up compared with those who were able to do less than 10 push-ups during the baseline exam.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Genetic vulnerability to menthol cigarette use

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A genetic variant found only in people of African descent significantly increases a smoker's preference for cigarettes containing menthol, a flavor additive. The variant of the MRGPRX4 gene is five to eight times more frequent among smokers who use menthol cigarettes than other smokers. The multi-ethnic study is the first to look across all genes to identify genetic vulnerability to menthol cigarettes.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Drug to rejuvenate muscle cells

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Researchers have developed a promising drug that has proven to significantly increase muscle size, strength and metabolic state in aged mice, according to a new study.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Cell study sheds light on damage caused by aging

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Some of the damaging cell effects linked to aging could be prevented by manipulating tiny parts of cells, a study shows.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Movement impairments in autism could be reversible

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Researchers from Cardiff University have established a link between a genetic mutation and developmental movement impairments in autism.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: When good cells go bad: Regulating the MS-causing properties of Th17 cells

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Multiple sclerosis (MS) and other inflammatory autoimmune diseases are characterized by localized inflammation in various tissues, including the brain. Using a mouse model of MS, a team has identified a major regulator of Th17 cell-associated pathogenic inflammatory processes. The protein, Satb1, enhances the expression of genes promoting inflammation and suppresses genes needed to prevent autoimmunity. By targeting this protein, novel therapies may be able to attenuate inflammatory autoimmune diseases.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: New therapy for aggressive blood cancer discovered

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Acute myeloid leukemia (AML) is the most common form of acute leukemia. It is characterized by an increase of malignant myeloid progenitor cells at the expense of mature blood cells. Only twenty-five percent of all AML patients survive five years beyond the initial diagnosis. Therefore there is an urgent need to deepen the knowledge about this form of blood cancer and to develop new therapeutic approaches.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Brain clock ticks differently in autism

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The neural 'time windows' in certain small brain areas contribute to the complex cognitive symptoms of autism, new research suggests. In a brain imaging study of adults, the severity of autistic symptoms was linked to how long these brain areas stored information. The differences in neural timescales may underlie features of autism like hypersensitivity and could be useful as a future diagnostic tool.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Even as hospitals cut risky antibiotic use in-house, patients often go home with them

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Even as hospitals try to cut back on prescribing powerful but risky antibiotics called fluoroquinolones, a new study shows that many patients still head home with prescriptions for the drugs -- increasing their risk of everything from 'superbug' infections to torn tendons. In fact, the hospitals that are actively trying to reduce inpatient fluoroquinolone use were twice as likely to discharge patients with a new prescription for one of them.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Balanced reporting of sports head injuries

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A group of more than 60 leading international neuroscientists are asking for balance when reporting on sports-related injury chronic traumatic encephalopathy (CTE).

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: How ****** tissue stiffening promotes ****** cancer development

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By examining how mammary cells respond in a stiffness-changing hydrogel, researchers discovered that several pathways work together to signal breast cells to turn cancerous. The work could inspire new approaches to treating patients and inhibiting tumor growth.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Fractures, head injuries common in e-scooter collisions

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UCLA researchers have found that people involved in electric scooter accidents are sometimes injured badly enough -- from fractures, dislocated joints and head injuries -- to require treatment in an emergency department.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Drinking and drug-use dreams in recovery tied to more severe addiction history

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Vivid dreams involving drinking and drug use are common among individuals in recovery. A study finds these relapse dreams are more common in those with more severe clinical histories of alcohol and other drug problems.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Uncovering the evolution of the brain

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What makes us human, and where does this mysterious property of 'humanness' come from? Humans are genetically similar to chimpanzees and bonobos, yet there exist obvious behavioral and cognitive differences. Now, researchers have developed a strategy to more easily study the early development of human neurons compared with the neurons of nonhuman primates.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Why too much DNA repair can injure tissue

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Researchers have discovered how overactive DNA repair systems can lead to retinal damage and blindness in mice. A DNA repair enzyme called Aag glycosylase becomes hyperactive, provoking an inflammatory response that produces necrosis, leading to severe tissue damage.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: With age comes hearing loss and a greater risk of cognitive decline

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In a new study, researchers report that hearing impairment is associated with accelerated cognitive decline with age, though the impact of mild hearing loss may be lessened by higher education.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Teaching self-driving cars to predict pedestrian movement

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By zeroing in on humans' gait, body symmetry and foot placement, researchers are teaching self-driving cars to recognize and predict pedestrian movements with greater precision than current technologies.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: Infection biology: What makes Helicobacter so adaptable?

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The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: More efficient system to reprogram stem cells

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Induced pluripotent stem cells, the workhorse of many regenerative medicine projects, start out as differentiated cells that are reprogrammed to pluripotent stem cells by exposure to a complex set of genetic cocktails.